CATH Domain 1v54A00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.210	Cytochrome C Oxidase; Chain A
	1.20.210.10	Cytochrome c oxidase-like, subunit I domain

Domain Context

CATH Clusters

Superfamily	Cytochrome c oxidase-like, subunit I domain
Functional Family	Cytochrome c oxidase subunit 1

Enzyme Information

1.9.3.1

Cytochrome-c oxidase.

based on mapping to UniProt P00396

4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.

-!- The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment. -!- Several bacteria appear to contain analogous oxidases.

UniProtKB Entries (1)

P10175

COX8B_BOVIN

Bos taurus

Cytochrome c oxidase subunit 8B, mitochondrial

PDB Structure

PDB	1V54
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process. Tsukihara, T., Shimokata, K., Katayama, Y., Shimada, H., Muramoto, K., Aoyama, H., Mochizuki, M., Shinzawa-Itoh, K., Yamashita, E., Yao, M., Ishimura, Y., Yoshikawa, S. Proc.Natl.Acad.Sci.Usa