CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.520 | Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 |
| Functional Family | NEDD8-activating enzyme E1 catalytic subunit |
Enzyme Information
| 6.2.1.- |
Acid--thiol ligases.
based on mapping to UniProt Q8TBC4
|
UniProtKB Entries (1)
| Q15843 |
NEDD8_HUMAN
Homo sapiens
NEDD8
|
PDB Structure
| PDB | 1R4M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell
|
