CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1240 | Phosphoglycerate mutase-like |
Domain Context
CATH Clusters
| Superfamily | Phosphoglycerate mutase-like |
| Functional Family | Prostatic acid phosphatase |
Enzyme Information
| 3.1.3.2 |
Acid phosphatase.
based on mapping to UniProt P15309
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.
|
| 3.1.3.5 |
5'-nucleotidase.
based on mapping to UniProt P15309
A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.
-!- Wide specificity for 5'-nucleotides.
|
UniProtKB Entries (1)
| P15309 |
PPAP_HUMAN
Homo sapiens
Prostatic acid phosphatase
|
PDB Structure
| PDB | 1ND6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of human prostatic acid phosphatase in complex with a
phosphate ion and alpha-benzylaminobenzylphosphonic acid update the
mechanistic picture and offer new insights into inhibitor design
Biochemistry
|