CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.290 | Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A |
|
3.10.290.10 | RNA-binding S4 domain |
Domain Context
CATH Clusters
| Superfamily | RNA-binding S4 domain |
| Functional Family | Pseudouridine synthase |
Enzyme Information
| 5.4.99.19 |
16S rRNA pseudouridine(516) synthase.
based on mapping to UniProt P0AA43
16S rRNA uridine(516) = 16S rRNA pseudouridine(516).
-!- The enzyme is specific for uridine(516) in 16S rRNA. -!- In vitro, the enzyme does not modify free 16S rRNA. -!- The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins.
|
UniProtKB Entries (1)
| P0AA43 |
RSUA_ECOLI
Escherichia coli K-12
Ribosomal small subunit pseudouridine synthase A
|
PDB Structure
| PDB | 1KSV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP.
Nat.Struct.Biol.
|
