CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
4 | Few Secondary Structures |
|
4.10 | Irregular |
|
4.10.460 | Inositol Polyphosphate 1-phosphatase; domain 1 |
|
4.10.460.10 | Inositol Polyphosphate 1-phosphatase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Inositol Polyphosphate 1-phosphatase, domain 1 |
| Functional Family | Inositol polyphosphate 1-phosphatase |
Enzyme Information
| 3.1.3.57 |
Inositol-1,4-bisphosphate 1-phosphatase.
based on mapping to UniProt P21327
1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D-myo-inositol 4-phosphate + phosphate.
-!- Acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar V(max) for both substrates, but with a 5 times higher affinity for the bisphosphate. -!- Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
|
UniProtKB Entries (1)
| P21327 |
INPP_BOVIN
Bos taurus
Inositol polyphosphate 1-phosphatase
|
PDB Structure
| PDB | 1INP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Spodoptera |
| Primary Citation |
Crystal structure of inositol polyphosphate 1-phosphatase at 2.3-A resolution.
Biochemistry
|
