1 keywords

CATH Domain 1i3zA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.505 SHC Adaptor Protein
Homologous Superfamily 3.30.505.10 SH2 domain

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family SH2 domain containing 1B

Enzyme Information

UniProtKB Entries (2)

O35324
SH21B_MOUSE
Mus musculus
SH2 domain-containing protein 1B
Q13291
SLAF1_HUMAN
Homo sapiens
Signaling lymphocytic activation molecule

PDB Structure

PDB 1I3Z
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells.
Morra, M., Lu, J., Poy, F., Martin, M., Sayos, J., Calpe, S., Gullo, C., Howie, D., Rietdijk, S., Thompson, A., Coyle, A.J., Denny, C., Yaffe, M.B., Engel, P., Eck, M.J., Terhorst, C.
Eur.J.Biochem.