CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family Crossover junction endodeoxyribonuclease RuvC

Enzyme Information

3.1.22.4
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt P0A814
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.

UniProtKB Entries (1)

P0A814
RUVC_ECOLI
Escherichia coli K-12
Crossover junction endodeoxyribonuclease RuvC

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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