CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family HLA class II histocompatibility antigen, DRB1-1 beta chain

Enzyme Information

4.1.1.15
Glutamate decarboxylase.
based on mapping to UniProt Q05329
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.

UniProtKB Entries (2)

Q31135
Q31135_MOUSE
Mus musculus
H2-Ab1 protein
Q05329
DCE2_HUMAN
Homo sapiens
Glutamate decarboxylase 2

PDB Structure

PDB 1ES0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes.
Corper, A.L., Stratmann, T., Apostolopoulos, V., Scott, C.A., Garcia, K.C., Kang, A.S., Wilson, I.A., Teyton, L.
Science