CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.140 | Nucleic acid-binding proteins |
Domain Context
CATH Clusters
| Superfamily | Nucleic acid-binding proteins |
| Functional Family | Aspartyl-tRNA synthetase, cytoplasmic |
Enzyme Information
| 6.1.1.12 |
Aspartate--tRNA ligase.
based on mapping to UniProt P04802
ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).
|
UniProtKB Entries (1)
| P04802 |
SYDC_YEAST
Saccharomyces cerevisiae S288C
Aspartate--tRNA ligase, cytoplasmic
|
PDB Structure
| PDB | 1EOV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
J.Mol.Biol.
|
