The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"HUPs
".
FunFam 89152: Cytoplasmic tRNA 2-thiolation protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
40 |
A2Q879 (/ISS)
A3GGB3 (/ISS)
A5DPQ4 (/ISS)
A5E3Q3 (/ISS)
A6ZTX8 (/ISS)
A7TER7 (/ISS)
A8PVM6 (/ISS)
A8WR63 (/ISS)
B0DK66 (/ISS)
B1WBV0 (/ISS)
(30 more) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
2 | O76365 (/IDA) P53088 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P53088 (/IPI) Q7Z7A3 (/IPI) |
|
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
|
1 | O94282 (/IPI) |
|
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
1 | O94282 (/ISM) |
|
Nucleotidyltransferase activity GO:0016779
Catalysis of the transfer of a nucleotidyl group to a reactant.
|
1 | P53088 (/IDA) |
|
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
|
1 | P76055 (/IDA) |
|
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
|
1 | O76365 (/IMP) |
|
4 iron, 4 sulfur cluster binding GO:0051539
Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
|
1 | P76055 (/IDA) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
|
41 |
A2Q879 (/ISS)
A3GGB3 (/ISS)
A5DPQ4 (/ISS)
A5E3Q3 (/ISS)
A6ZTX8 (/ISS)
A7TER7 (/ISS)
A8PVM6 (/ISS)
A8WR63 (/ISS)
B0DK66 (/ISS)
B1WBV0 (/ISS)
(31 more) |
|
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
|
40 |
A2Q879 (/ISS)
A3GGB3 (/ISS)
A5DPQ4 (/ISS)
A5E3Q3 (/ISS)
A6ZTX8 (/ISS)
A7TER7 (/ISS)
A8PVM6 (/ISS)
A8WR63 (/ISS)
B0DK66 (/ISS)
B1WBV0 (/ISS)
(30 more) |
|
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
|
2 | O76365 (/IMP) P53088 (/IMP) |
|
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
|
2 | O94282 (/IMP) P53088 (/IMP) |
|
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
|
2 | O76365 (/IMP) P53088 (/IMP) |
|
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
|
1 | O76365 (/IGI) |
|
TRNA wobble uridine modification GO:0002098
The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
|
1 | Q7Z7A3 (/NAS) |
|
Cytoplasmic translational elongation GO:0002182
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
|
1 | O94282 (/NAS) |
|
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
|
1 | P76055 (/IMP) |
|
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
|
1 | Q7Z7A3 (/TAS) |
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
1 | O76365 (/IGI) |
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
1 | O76365 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | O76365 (/IGI) |
|
Protein urmylation GO:0032447
Covalent attachment of the ubiquitin-like protein URM1 to another protein.
|
1 | P53088 (/IMP) |
|
Protein urmylation GO:0032447
Covalent attachment of the ubiquitin-like protein URM1 to another protein.
|
1 | O94282 (/ISO) |
|
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
|
1 | P76055 (/IDA) |
|
TRNA thio-modification GO:0034227
The addition a sulfur atom to a nucleotide in a tRNA molecule.
|
1 | Q7Z7A3 (/NAS) |
|
Vulval development GO:0040025
The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
1 | O76365 (/IGI) |
|
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
1 | O76365 (/IGI) |
|
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | O76365 (/IGI) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
41 |
A2Q879 (/ISS)
A3GGB3 (/ISS)
A5DPQ4 (/ISS)
A5E3Q3 (/ISS)
A6ZTX8 (/ISS)
A7TER7 (/ISS)
A8PVM6 (/ISS)
A8WR63 (/ISS)
B0DK66 (/ISS)
B1WBV0 (/ISS)
(31 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P53088 (/IDA) P76055 (/IDA) |
|
Cytosolic tRNA wobble base thiouridylase complex GO:0002144
A complex of two proteins involved in the thiolation of U34 in glutamate, lysine, and glutamine tRNAs of eukaryotes.
|
1 | O94282 (/IPI) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q99J10 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q7Z7A3 (/TAS) |
