View in Gene3D

CATH Superfamily 3.40.50.620

HUPs

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 88425: Sulfate adenylyltransferase domain-containing prot...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sulfate adenylyltransferase. [EC: 2.7.7.4]
ATP + sulfate = diphosphate + adenylyl sulfate.
  • The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.
  • This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
 4784 A0A010SAB3 A0A010SAB3 A0A015JW94 A0A015JW94 A0A015NZ05 A0A015NZ05 A0A016QLU0 A0A016QLU0 A0A017HTZ0 A0A017HTZ0
(4774 more...)
Adenylyl-sulfate kinase. [EC: 2.7.1.25]
ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate.
  • The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.
  • This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25.
 662 A0A017HAH9 A0A017HAH9 A0A017HTZ0 A0A017HTZ0 A0A022VTC0 A0A022VTC0 A0A022XJQ1 A0A022XJQ1 A0A023NPI9 A0A023NPI9
(652 more...)
Pyruvate kinase. [EC: 2.7.1.40]
ATP + pyruvate = ADP + phosphoenolpyruvate.
  • UTP, GTP, CTP, ITP and dATP can also act as donors.
  • Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
 40 A0A0G1I5J0 A0A0G1I5J0 A0A0G1IMN5 A0A0G1IMN5 A0A0G1QZH4 A0A0G1QZH4 A0A0G1V7F8 A0A0G1V7F8 A0A0H4T6D5 A0A0H4T6D5
(30 more...)
Cellulase. [EC: 3.2.1.4]
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
  • Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.
 4 A0A078I3S0 A0A078I3S0 A0A0D3CBP7 A0A0D3CBP7
CATH-Gene3D is a Global Biodata Core Resource Learn more...