The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HUPs
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 87828: Glutamate--tRNA ligase 1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate--tRNA ligase. [EC: 6.1.1.17]
ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
    332 A0A017HE64 A0A017HP24 A0A024LQK7 A0A031I8J8 A0A031JDI8 A0A031K7B0 A0A060QAL6 A0A060QIV4 A0A061Q966 A0A066PQN7
    (322 more...)
    Non-chaperonin molecular chaperone ATPase. [EC: 3.6.4.10]
    ATP + H(2)O = ADP + phosphate.
    • This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins.
    • They comprise a number of heat-shock-cognate proteins.
    • They are also active in clathrin uncoating and in the oligomerization of actin.
    16 A0A0E1X2G2 A0A0M2Y6V2 A5VQR9 A9M5G0 B0CGU5 C0G6N1 C0RJB6 C4IRK0 C4WJR1 C7LC98
    (6 more...)
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