View in Gene3D

CATH Superfamily 3.40.50.300

P-loop containing nucleotide triphosphate hydrolases

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
P-loop containing nucleotide triphosphate hydrolases
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 628076: Probable cobyric acid synthase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenosylcobyric acid synthase (glutamine-hydrolyzing). [EC: 6.3.5.10]
4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H(2)O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate.
  • NH(3) can act instead of glutamine.
  • This enzyme catalyzes the four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of cobyrinic acid triamide, tetraamide and pentaamide intermediates.
 38 A0A075FRR2 A0A075GXG8 A0A075GZQ9 A0A075H1W2 A0A075HJI2 A0A075HX82 A0A075HXP5 A0A075I5A8 A0A087RZV7 A0A160TI50
(28 more...)
Threonine-phosphate decarboxylase. [EC: 4.1.1.81]
L-threonine O-3-phosphate = (R)-1-aminopropan-2-yl phosphate + CO(2).
  • Unable to decarboxylate the D-isomer of threonine O-3-phosphate.
  • The product of this reaction, (R)-1-aminopropan-2-yl phosphate, is the substrate of EC 6.3.1.10, which converts adenosylcobyric acid into adenosylcobinamide phosphate in the anaerobic cobalamin biosynthesis pathway.
 1 Q8EXQ7
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase. [EC: 2.4.2.21]
Beta-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole = nicotinate + alpha-ribazole 5'-phosphate.
  • Also acts on benzimidazole, and the clostridial enzyme acts on adenine to form 7-alpha-D-ribosyladenine 5'-phosphate.
  • The product of the reaction, alpha-ribazole 5'-phosphate, forms part of the corrin biosynthesis pathway and is a substrate for EC 2.7.8.2.
  • It can also be dephosphorylated to form alpha-ribazole by the action of EC 3.1.3.73.
 1 A0A0B0HN54
CATH-Gene3D is a Global Biodata Core Resource Learn more...