CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Ras family small GTPase

Enzyme Information

3.6.5.2
Small monomeric GTPase.
based on mapping to UniProt Q76NM4
GTP + H(2)O = GDP + phosphate.
-!- A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the alpha-subunit of EC 3.6.1.46. -!- Involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). -!- Formerly EC 3.6.1.47.

UniProtKB Entries (1)

Q76NM4
Q76NM4_PLAF7
Plasmodium falciparum 3D7
Ras-related protein Rab-11A

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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