CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Cystic fibrosis transmembrane conductance regulator |
Enzyme Information
| 3.6.3.49 |
Channel-conductance-controlling ATPase.
based on mapping to UniProt P13569
ATP + H(2)O = ADP + phosphate.
-!- An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. -!- It is also involved in the functioning of other transmembrane channels.
|
UniProtKB Entries (1)
| P13569 |
CFTR_HUMAN
Homo sapiens
Cystic fibrosis transmembrane conductance regulator
|
PDB Structure
| PDB | |
| External Links | |
| Method | |
| Organism | |
| Primary Citation |
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