CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Exonuclease V subunit gamma |
Enzyme Information
| 3.1.11.5 |
Exodeoxyribonuclease V.
based on mapping to UniProt P07648
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.
-!- Preference for double-stranded DNA. -!- Possesses DNA-dependent ATPase activity. -!- Acts endonucleolytically on single-stranded circular DNA. -!- Similar enzyme: Haemophilus influenzae ATP-dependent DNase.
|
UniProtKB Entries (1)
| P08394 |
RECB_ECOLI
Escherichia coli K-12
RecBCD enzyme subunit RecB
|
PDB Structure
| PDB | 1W36 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Recbcd Enzyme Reveals a Machine for Processing DNA Breaks
Nature
|
