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CATH Superfamily 3.40.50.11610

Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2-oxoglutarate dehydrogenase E1 component
339
3D
 2jgdB04 - 85.6
2
2-oxoglutarate dehydrogenase E1 component
225
3D
 6i2sA04 - 93.0
3
2-oxoglutarate dehydrogenase, isoform X4
176 - - 79.1
4
2-oxoglutarate dehydrogenase, mitochondrial isoform X1
172 - - 74.8
5
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
141 - - 87.0
6
2-oxoglutarate dehydrogenase, mitochondrial
97 - - 77.4
7
2-oxoglutarate dehydrogenase, E1 component
76 - - 75.9
8
2-oxoglutarate dehydrogenase, mitochondrial isoform X4
46 - - 73.7
9
2-oxoglutarate dehydrogenase E1 component
38 - - 91.4
10
Oxoglutarate dehydrogenase
Succinyl-transferring
17 - - 5.4
11
Oxoglutarate dehydrogenase
Succinyl-transferring
16 - - 44.5
12
2-oxoglutarate dehydrogenase E1 component
14 - - 37.1
13
Uncharacterized protein, isoform B
12 - - 18.9
14
Oxoglutarate
alpha-ketoglutarate lipoamide
10 - - 76.5
16
2-oxoglutarate dehydrogenase E1 component,putative
8 - - 34.4
15
Putative 2-oxoglutarate dehydrogenase subunit
8 - - 37.6
17
2-oxoglutarate dehydrogenase, mitochondrial
6 - - 69.8
20
3 - - 24.8
18
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial
3 - - 11.9
19
Alpha-ketoglutarate dehydrogenase E1
3 - - 5.9
22
2 - - 0.0
25
2 - - 0.0
21
2 - - 15.1
23
2 - - 0.0
24
2 - - 41.0
29
1 - - 0.0
39
1 - - 0.0
26
1 - - 0.0
37
1 - - 0.0
33
1 - - 0.0
30
1 - - 0.0
32
1 - - 0.0
34
1 - - 0.0
36
1 - - 0.0
31
1 - - 0.0
27
1 - - 0.0
40
1 - - 0.0
38
1 - - 0.0
28
1 - - 0.0
35
1 - - 0.0