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CATH Superfamily 1.10.506.10

GTPase Activation - p120gap; domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GTPase Activation - p120gap; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Ras GTPase-activating protein nGAP isoform 2
1127
3D
 3bxjB03 - 65.3
2
Ras GTPase-activating protein nGAP isoform 2
963 - - 80.8
3
Plexin A2
451
3D
 3ig3A01 - 73.1
4
IQ motif containing GTPase activating protein 1
423
3D
 3fayA00 - 95.4
5
Plexin A1
341
3D
 3rytB01 - 56.4
6
Plexin A1
325 - - 76.8
7
RAS p21 protein activator 1
287
3D
 1wq1G01 - 59.7
8
RAS p21 protein activator 1
273
3D
 1wq1G02 - 69.4
9
GTPase-activating protein and VPS9 domain-containing protein 1 isoform X1
253 - - 47.8
10
Plexin B1
234 - - 70.1
11
Ras GTPase-activating protein 2 isoform 3
212 - - 75.5
12
Plexin B1
208 - - 75.3
13
Plexin b1a
198
3D
 3su8X01 - 75.7
14
Neurofibromin 1
192
3D
 1nf1A01 - 19.9
15
Neurofibromin isoform 1
186 - - 38.7
16
Neurofibromin 1
184 - - 40.6
17
Neurofibromin 1
179 - - 48.3
18
Plexin B2
162 - - 58.0
19
Neurofibromin 1
142 - - 54.7
20
Ras GTPase-activating protein 4 isoform 1
133 - - 68.9
21
Plexin C1
124
3D
 4m8nD01 - 68.2
22
neurofibromin isoform X1
97 - - 32.1
23
Neurofibromin isoform 1
93
3D
 1nf1A02 - 50.7
24
Plexin D1
83 - - 58.2
25
Plexin D1
80 - - 34.6
26
Plexin D1
67 - - 39.6
27
Plexin A, isoform B
62 - - 81.6
28
RAS p21 protein activator 3
56 - - 42.9
29
probable Ras GTPase-activating protein isoform X2
55 - - 16.6
30
probable Ras GTPase-activating protein isoform X8
53 - - 47.7
31
RAS protein activator like 3
51 - - 22.6
32
RAS protein activator like-3
50 - - 43.5
33
PLeXin
20 - - 68.9
34
IRA1p GTPase-activating protein
17 - - 69.2
35
Plexin b2a
17 - - 28.8
36
PLeXin
14 - - 32.9
37
GTPase-activating protein isoform X2
13 - - 14.1
39
Plexin-2
9 - - 16.4
38
Bud2p
9 - - 1.1
40
Plexin-2
8 - - 16.9
41
Ras GTPase-activating-like protein IQG1
7 - - 0.3
42
Plexin b2a
7 - - 14.4
43
Plexin C1
6 - - 7.6
46
Uncharacterized protein
5 - - 40.4
44
Plexin A3
5 - - 57.3
45
Receptor-mediated endocytosis protein 6 homolog
5 - - 14.2
47
Uncharacterized protein
5 - - 65.1
48
Uncharacterized protein
4 - - 15.3
49
Uncharacterized protein
4 - - 36.8
50
Uncharacterized protein
4 - - 82.3
51
Receptor-mediated endocytosis protein 6
3 - - 17.3
53
Plexin A2
3 - - 17.9
55
Ras GTPase-activating-like protein, IQGAP family member, putative
3 - - 3.1
52
GTPase activating protein involved in bud site selection, putative
3 - - 3.2
54
Plexin-A1
3 - - 15.3
60
Uncharacterized protein
2 - - 36.7
62
Uncharacterized protein
2 - - 16.8
56
Probable Ras GTPase-activating-like protein ngap
2 - - 6.2
58
Ras GTPase-activating protein
2 - - 4.6
65
Uncharacterized protein
2 - - 10.4
67
Uncharacterized protein
2 - - 10.4
61
Plexin B3
2 - - 41.0
63
Ras GTPase-activating protein gap-1
2 - - 10.4
57
Probable Ras GTPase-activating-like protein ngap
2 - - 12.1
64
Plexin A3
2 - - 5.2
66
Uncharacterized protein
2 - - 3.5
59
Plexin A
2 - - 0.0
78
Plexin C1
1 - - 0.0
89
Uncharacterized protein
1 - - 0.0
80
Uncharacterized protein
1 - - 0.0
92
Uncharacterized protein
1 - - 0.0
105
Uncharacterized protein
1 - - 0.0
82
Uncharacterized protein
1 - - 0.0
69
Uncharacterized protein
1 - - 0.0
99
Uncharacterized protein
1 - - 0.0
90
Uncharacterized protein
1 - - 0.0
76
Folate gamma-glutamyl hydrolase
1 - - 0.0
84
Uncharacterized protein
1 - - 0.0
103
Uncharacterized protein
1 - - 0.0
71
Uncharacterized protein
1 - - 0.0
96
Uncharacterized protein
1 - - 0.0
85
Uncharacterized protein
1 - - 0.0
74
Uncharacterized protein
1 - - 0.0
94
Uncharacterized protein
1 - - 0.0
98
LD15833p
1 - - 0.0
87
Uncharacterized protein
1 - - 0.0
72
Plexin B3
1 - - 0.0
91
Uncharacterized protein
1 - - 0.0
68
Uncharacterized protein
1 - - 0.0
81
Uncharacterized protein
1 - - 0.0
102
Neurofibromin-A
1 - - 0.0
77
Uncharacterized protein
1 - - 0.0
100
Uncharacterized protein
1 - - 0.0
79
Uncharacterized protein
1 - - 0.0
93
Uncharacterized protein
1 - - 0.0
83
Uncharacterized protein
1 - - 0.0
70
Uncharacterized protein
1 - - 0.0
101
Uncharacterized protein
1 - - 0.0
95
Uncharacterized protein
1 - - 0.0
86
Predicted protein
1 - - 0.0
75
Predicted protein
1 - - 0.0
73
Uncharacterized protein
1 - - 0.0
104
Plexin A1
1 - - 0.0
97
Uncharacterized protein
1 - - 0.0
88
Uncharacterized protein
1 - - 0.0