CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Methylosome protein 50

Enzyme Information

UniProtKB Entries (1)

Q9BQA1
MEP50_HUMAN
Homo sapiens
Methylosome protein 50

PDB Structure

PDB 6CKC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
Bonday, Z.Q., Cortez, G.S., Grogan, M.J., Antonysamy, S., Weichert, K., Bocchinfuso, W.P., Li, F., Kennedy, S., Li, B., Mader, M.M., Arrowsmith, C.H., Brown, P.J., Eram, M.S., Szewczyk, M.M., Barsyte-Lovejoy, D., Vedadi, M., Guccione, E., Campbell, R.M.
ACS Med Chem Lett