CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Choline kinase alpha

Enzyme Information

2.7.1.82
Ethanolamine kinase.
based on mapping to UniProt P35790
ATP + ethanolamine = ADP + O-phosphoethanolamine.
2.7.1.32
Choline kinase.
based on mapping to UniProt P35790
ATP + choline = ADP + phosphocholine.
-!- Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.

UniProtKB Entries (1)

P35790
CHKA_HUMAN
Homo sapiens
Choline kinase alpha

PDB Structure

PDB 5W6O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a Unique Inhibitor-Binding Site on Choline Kinase alpha.
Kall, S.L., Delikatny, E.J., Lavie, A.
Biochemistry
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