CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.30 | Roll | |
2.30.29 | PH-domain like | |
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Functional Family | Myotubularin related protein 6 |
Enzyme Information
3.1.3.64 |
Phosphatidylinositol-3-phosphatase.
based on mapping to UniProt Q9Y217
1-phosphatidyl-1D-myo-inositol 3-phosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol + phosphate.
-!- This enzyme still works when the 2,3-bis(acyloxy)propyl group is removed, i.e., it hydrolyzes Ins(1,3)P(2) to Ins-1-P. -!- Formerly EC 3.1.3.65.
|
3.1.3.95 |
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase.
based on mapping to UniProt Q9Y217
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol 5-phosphate + phosphate.
-!- The enzyme is found in both plants and animals. -!- It also has the activity of EC 3.1.3.64.
|
UniProtKB Entries (1)
Q9Y217 |
MTMR6_HUMAN
Homo sapiens
Myotubularin-related protein 6
|
PDB Structure
PDB | 2YF0 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structure of Human Mtmr6
To be Published
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