CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Choline kinase alpha

Enzyme Information

2.7.1.82
Ethanolamine kinase.
based on mapping to UniProt P35790
ATP + ethanolamine = ADP + O-phosphoethanolamine.
2.7.1.32
Choline kinase.
based on mapping to UniProt P35790
ATP + choline = ADP + phosphocholine.
-!- Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.

UniProtKB Entries (1)

P35790
CHKA_HUMAN
Homo sapiens
Choline kinase alpha

PDB Structure

PDB 2CKO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
Malito, E., Sekulic, N., Too, W.C., Konrad, M., Lavie, A.
J.Mol.Biol.
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