PDB 6mbp

PDB Information

PDB6MBP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure.
Milite, C., Feoli, A., Horton, J.R., Rescigno, D., Cipriano, A., Pisapia, V., Viviano, M., Pepe, G., Amendola, G., Novellino, E., Cosconati, S., Cheng, X., Castellano, S., Sbardella, G.
J. Med. Chem.
HeaderTransferase/Transferase Inhbitor
Released2018-08-30
Resolution1.950
CATH Insert Date03 Mar, 2019

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped
B 03 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6mbpA00 04 Mar, 2019 2.170.270.10 Assigned
6mbpB00 04 Mar, 2019 2.170.270.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H9B1 EHMT1_HUMAN Homo sapiens Histone-lysine N-methyltransferase EHMT1
Q9H9B1 EHMT1_HUMAN Homo sapiens Histone-lysine N-methyltransferase EHMT1
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