PDB 6hx8

PDB Information

PDB6HX8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure.
Dohle, W., Prota, A.E., Menchon, G., Hamel, E., Steinmetz, M.O., Potter, B.V.L.
ACS Omega
HeaderCell Cycle
Released2018-10-16
Resolution2.400
CATH Insert Date03 Mar, 2019

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 03 Mar, 2019 Chopped
B 03 Mar, 2019 Chopped
C 03 Mar, 2019 Chopped
D 03 Mar, 2019 Chopped
E 03 Mar, 2019 Chopped
F 03 Mar, 2019 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6hx8A01 04 Mar, 2019 3.40.50.1440 Assigned
6hx8A02 04 Mar, 2019 3.30.1330.20 Assigned
6hx8A03 04 Mar, 2019 1.10.287.600 Assigned
6hx8B01 04 Mar, 2019 3.40.50.1440 Assigned
6hx8B02 04 Mar, 2019 3.30.1330.20 Assigned
6hx8B03 04 Mar, 2019 1.10.287.600 Assigned
6hx8C01 04 Mar, 2019 3.40.50.1440 Assigned
6hx8C02 04 Mar, 2019 3.30.1330.20 Assigned
6hx8C03 04 Mar, 2019 1.10.287.600 Assigned
6hx8D01 04 Mar, 2019 3.40.50.1440 Assigned
6hx8D02 04 Mar, 2019 3.30.1330.20 Assigned
6hx8D03 04 Mar, 2019 1.10.287.600 Assigned
6hx8E01 04 Mar, 2019 6.10.280.30 Assigned
6hx8F01 04 Mar, 2019 3.40.50.11480 Assigned
6hx8F02 04 Mar, 2019 3.30.470.20 Assigned
6hx8F03 04 Mar, 2019 Holding pen

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein