CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1440 | Tubulin/FtsZ, GTPase domain |
Domain Context
CATH Clusters
| Superfamily | Tubulin/FtsZ, GTPase domain |
| Functional Family | Tubulin alpha chain |
Enzyme Information
UniProtKB Entries (3)
| E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
| P63043 |
STMN4_RAT
Rattus norvegicus
Stathmin-4
|
| P81947 |
TBA1B_BOVIN
Bos taurus
Tubulin alpha-1B chain
|
PDB Structure
| PDB | 6HX8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocrystal Structure.
ACS Omega
|