PDB 6gfx

PDB Links
Overview

PDB Information

PDB	6GFX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21
Gene Source	Homo sapiens
Primary Citation	3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation. Testa, A., Lucas, X., Castro, G.V., Chan, K.H., Wright, J.E., Runcie, A.C., Gadd, M.S., Harrison, W.T.A., Ko, E.J., Fletcher, D., Ciulli, A. J. Am. Chem. Soc.
Header	Ligase
Released	2018-05-02
Resolution	1.830
CATH Insert Date	16 Jul, 2018

PDB Images (9)

Image of CATH 6gfx

6gfx

PDB 6gfx

Image of CATH 6gfxA

6gfxA

PDB Chain 6gfxA

Image of CATH 6gfxB

6gfxB

PDB Chain 6gfxB

Image of CATH 6gfxC

6gfxC

PDB Chain 6gfxC

Image of CATH 6gfxD

6gfxD

PDB Chain 6gfxD

Image of CATH 6gfxA00

6gfxA00

CATH Domain 6gfxA00

Image of CATH 6gfxB00

6gfxB00

CATH Domain 6gfxB00

Image of CATH 6gfxC01

6gfxC01

CATH Domain 6gfxC01

Image of CATH 6gfxC02

6gfxC02

CATH Domain 6gfxC02

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	16 Jul, 2018	Chopped
B	16 Jul, 2018	Chopped
C	16 Jul, 2018	Chopped
D	16 Jul, 2018	Rejected

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6gfxA00	19 Jul, 2018	3.10.20.90	Assigned
6gfxB00	19 Jul, 2018	3.30.710.10	Assigned
6gfxC01	19 Jul, 2018	2.60.40.780	Assigned
6gfxC02	19 Jul, 2018	1.10.750.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q16665	HIF1A_HUMAN	Homo sapiens	Hypoxia-inducible factor 1-alpha
Q15369	ELOC_HUMAN	Homo sapiens	Elongin-C
Q15370	ELOB_HUMAN	Homo sapiens	Elongin-B
P40337	VHL_HUMAN	Homo sapiens	von Hippel-Lindau disease tumor suppressor