CATH Domain 6gfxC02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.750	Elongin C; Chain C, domain 1
	1.10.750.10	von Hippel-Lindau disease tumour suppressor, alpha domain

Domain Context

CATH Clusters

Superfamily	von Hippel-Lindau disease tumour suppressor, alpha domain
Functional Family	von Hippel-Lindau disease tumor suppressor

Enzyme Information

UniProtKB Entries (1)

VHL_HUMAN

Homo sapiens

Von Hippel-Lindau disease tumor suppressor

PDB Structure

PDB	6GFX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation. Testa, A., Lucas, X., Castro, G.V., Chan, K.H., Wright, J.E., Runcie, A.C., Gadd, M.S., Harrison, W.T.A., Ko, E.J., Fletcher, D., Ciulli, A. J. Am. Chem. Soc.