PDB Information

PDB6DXL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Ramanjulu, J.M., Pesiridis, G.S., Yang, J., Concha, N., Singhaus, R., Zhang, S.Y., Tran, J.L., Moore, P., Lehmann, S., Eberl, H.C., Muelbaier, M., Schneck, J.L., Clemens, J., Adam, M., Mehlmann, J., Romano, J., Morales, A., Kang, J., Leister, L., Graybill, T.L., Charnley, A.K., Ye, G., Nevins, N., Behnia, K., Wolf, A.I., Kasparcova, V., Nurse, K., Wang, L., Li, Y., Klein, M., Hopson, C.B., Guss, J., Bantscheff, M., Bergamini, G., Reilly, M.A., Lian, Y., Duffy, K.J., Adams, J., Foley, K.P., Gough, P.J., Marquis, R.W., Smothers, J., Hoos, A., Bertin, J.
Nature
HeaderImmune System/Agonist
Released2018-06-29
Resolution2.450
CATH Insert Date16 Dec, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6dxlA01 28 Feb, 2019 Holding pen
6dxlA02 28 Feb, 2019 3.40.50.12100 Assigned
6dxlB01 28 Feb, 2019 Holding pen
6dxlB02 28 Feb, 2019 3.40.50.12100 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q86WV6 STING_HUMAN Homo sapiens Stimulator of interferon genes protein
Q86WV6 STING_HUMAN Homo sapiens Stimulator of interferon genes protein
CATH-Gene3D is a Global Biodata Core Resource Learn more...