CATH Domain 6dxlB02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.12100	Stimulator of interferon genes protein

Domain Context

CATH Clusters

Superfamily	Stimulator of interferon genes protein
Functional Family	Stimulator of interferon genes protein

Enzyme Information

UniProtKB Entries (1)

STING_HUMAN

Homo sapiens

Stimulator of interferon genes protein

PDB Structure

PDB	6DXL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Design of amidobenzimidazole STING receptor agonists with systemic activity. Ramanjulu, J.M., Pesiridis, G.S., Yang, J., Concha, N., Singhaus, R., Zhang, S.Y., Tran, J.L., Moore, P., Lehmann, S., Eberl, H.C., Muelbaier, M., Schneck, J.L., Clemens, J., Adam, M., Mehlmann, J., Romano, J., Morales, A., Kang, J., Leister, L., Graybill, T.L., Charnley, A.K., Ye, G., Nevins, N., Behnia, K., Wolf, A.I., Kasparcova, V., Nurse, K., Wang, L., Li, Y., Klein, M., Hopson, C.B., Guss, J., Bantscheff, M., Bergamini, G., Reilly, M.A., Lian, Y., Duffy, K.J., Adams, J., Foley, K.P., Gough, P.J., Marquis, R.W., Smothers, J., Hoos, A., Bertin, J. Nature