PDB 6dar

PDB Information

PDB6DAR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.
Wang, F., Jeon, K.O., Salovich, J.M., Macdonald, J.D., Alvarado, J., Gogliotti, R.D., Phan, J., Olejniczak, E.T., Sun, Q., Wang, S., Camper, D., Yuh, J.P., Shaw, J.G., Sai, J., Rossanese, O.W., Tansey, W.P., Stauffer, S.R., Fesik, S.W.
J. Med. Chem.
HeaderDna Binding Protein/Inhibitor
Released2018-05-01
Resolution1.880
CATH Insert Date09 Sep, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Sep, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6darA00 10 Sep, 2018 2.130.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
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