CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family WD repeat-containing protein 5

Enzyme Information

UniProtKB Entries (1)

P61964
WDR5_HUMAN
Homo sapiens
WD repeat-containing protein 5

PDB Structure

PDB 6DAR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.
Wang, F., Jeon, K.O., Salovich, J.M., Macdonald, J.D., Alvarado, J., Gogliotti, R.D., Phan, J., Olejniczak, E.T., Sun, Q., Wang, S., Camper, D., Yuh, J.P., Shaw, J.G., Sai, J., Rossanese, O.W., Tansey, W.P., Stauffer, S.R., Fesik, S.W.
J. Med. Chem.
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