PDB 6d88

PDB Information

PDB6D88
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
Wang, Q., Arnst, K.E., Wang, Y., Kumar, G., Ma, D., Chen, H., Wu, Z., Yang, J., White, S.W., Miller, D.D., Li, W.
J. Med. Chem.
HeaderCell Cycle
Released2018-04-26
Resolution2.850
CATH Insert Date16 Sep, 2018

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2018 Chopped
B 16 Sep, 2018 Chopped
C 16 Sep, 2018 Chopped
D 16 Sep, 2018 Chopped
E 16 Sep, 2018 Chopped
F 16 Sep, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6d88A01 17 Sep, 2018 3.40.50.1440 Assigned
6d88A02 17 Sep, 2018 3.30.1330.20 Assigned
6d88A03 17 Sep, 2018 1.10.287.600 Assigned
6d88B01 17 Sep, 2018 3.40.50.1440 Assigned
6d88B02 17 Sep, 2018 3.30.1330.20 Assigned
6d88B03 17 Sep, 2018 1.10.287.600 Assigned
6d88C01 17 Sep, 2018 3.40.50.1440 Assigned
6d88C02 17 Sep, 2018 3.30.1330.20 Assigned
6d88C03 17 Sep, 2018 1.10.287.600 Assigned
6d88D01 17 Sep, 2018 3.40.50.1440 Assigned
6d88D02 17 Sep, 2018 3.30.1330.20 Assigned
6d88D03 17 Sep, 2018 1.10.287.600 Assigned
6d88E01 17 Sep, 2018 6.10.280.30 Assigned
6d88F01 17 Sep, 2018 3.40.50.11480 Assigned
6d88F02 17 Sep, 2018 3.30.470.20 Assigned
6d88F03 17 Sep, 2018 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
P02554 TBB_PIG Sus scrofa Tubulin beta chain
Q2XVP4 TBA1B_PIG Sus scrofa Tubulin alpha-1B chain
P02554 TBB_PIG Sus scrofa Tubulin beta chain
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