CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.1440 | Tubulin/FtsZ, GTPase domain |
Domain Context
CATH Clusters
Superfamily | Tubulin/FtsZ, GTPase domain |
Functional Family | Tubulin beta chain |
Enzyme Information
UniProtKB Entries (3)
P63043 |
STMN4_RAT
Rattus norvegicus
Stathmin-4
|
E1BQ43 |
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
|
P02554 |
TBB_PIG
Sus scrofa
Tubulin beta chain
|
PDB Structure
PDB | 6D88 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities.
J. Med. Chem.
|