PDB 6d59

PDB Links
Overview

PDB Information

PDB	6D59
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. Hodges, T.R., Abbott, J.R., Little, A.J., Sarkar, D., Salovich, J.M., Howes, J.E., Akan, D.T., Sai, J., Arnold, A.L., Browning, C., Burns, M.C., Sobolik, T., Sun, Q., Beesetty, Y., Coker, J.A., Scharn, D., Stadtmueller, H., Rossanese, O.W., Phan, J., Waterson, A.G., McConnell, D.B., Fesik, S.W. J. Med. Chem.
Header	Signaling Protein
Released	2018-04-19
Resolution	1.700
CATH Insert Date	23 Sep, 2018

PDB Images (8)

Image of CATH 6d59

6d59

PDB 6d59

Image of CATH 6d59A

6d59A

PDB Chain 6d59A

Image of CATH 6d59B

6d59B

PDB Chain 6d59B

Image of CATH 6d59C

6d59C

PDB Chain 6d59C

Image of CATH 6d59A00

6d59A00

CATH Domain 6d59A00

Image of CATH 6d59B01

6d59B01

CATH Domain 6d59B01

Image of CATH 6d59B02

6d59B02

CATH Domain 6d59B02

Image of CATH 6d59C00

6d59C00

CATH Domain 6d59C00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	23 Sep, 2018	Chopped
B	23 Sep, 2018	Chopped
C	23 Sep, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6d59A00	24 Sep, 2018	3.40.50.300	Assigned
6d59B01	24 Sep, 2018	1.20.870.10	Assigned
6d59B02	24 Sep, 2018	1.10.840.10	Assigned
6d59C00	24 Sep, 2018	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1