PDB 6c3e

PDB Links
Overview

PDB Information

PDB	6C3E
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships. Yoshikawa, M., Saitoh, M., Katoh, T., Seki, T., Bigi, S.V., Shimizu, Y., Ishii, T., Okai, T., Kuno, M., Hattori, H., Watanabe, E., Saikatendu, K.S., Zou, H., Nakakariya, M., Tatamiya, T., Nakada, Y., Yogo, T. J. Med. Chem.
Header	Transferase/Transferase Inhibitor
Released	2018-01-09
Resolution	2.600
CATH Insert Date	03 Jun, 2018

PDB Images (7)

Image of CATH 6c3e

6c3e

PDB 6c3e

Image of CATH 6c3eA

6c3eA

PDB Chain 6c3eA

Image of CATH 6c3eB

6c3eB

PDB Chain 6c3eB

Image of CATH 6c3eA01

6c3eA01

CATH Domain 6c3eA01

Image of CATH 6c3eA02

6c3eA02

CATH Domain 6c3eA02

Image of CATH 6c3eB01

6c3eB01

CATH Domain 6c3eB01

Image of CATH 6c3eB02

6c3eB02

CATH Domain 6c3eB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped
B	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6c3eA01	28 Jun, 2018	3.30.200.20	Assigned
6c3eA02	28 Jun, 2018	1.10.510.10	Assigned
6c3eB01	28 Jun, 2018	3.30.200.20	Assigned
6c3eB02	28 Jun, 2018	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q13546	RIPK1_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 1
Q13546	RIPK1_HUMAN	Homo sapiens	Receptor-interacting serine/threonine-protein kinase 1