PDB Information

PDB6BWK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.
Petrie, E.J., Sandow, J.J., Jacobsen, A.V., Smith, B.J., Griffin, M.D.W., Lucet, I.S., Dai, W., Young, S.N., Tanzer, M.C., Wardak, A., Liang, L.Y., Cowan, A.D., Hildebrand, J.M., Kersten, W.J.A., Lessene, G., Silke, J., Czabotar, P.E., Webb, A.I., Murphy, J.M.
Nat Commun
HeaderTransferase
Released2017-12-15
Resolution2.790
CATH Insert Date06 Jul, 2018

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6bwkA01 19 Jul, 2018 3.30.200.20 Assigned
6bwkA02 19 Jul, 2018 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8NB16 MLKL_HUMAN Homo sapiens Mixed lineage kinase domain-like protein
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