PDB 6bn8

PDB Information

PDB6BN8
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nowak, R.P., DeAngelo, S.L., Buckley, D., He, Z., Donovan, K.A., An, J., Safaee, N., Jedrychowski, M.P., Ponthier, C.M., Ishoey, M., Zhang, T., Mancias, J.D., Gray, N.S., Bradner, J.E., Fischer, E.S.
Nat. Chem. Biol.
HeaderLigase
Released2017-11-16
Resolution3.990
CATH Insert Date06 Jul, 2018

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped
C 06 Jul, 2018 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
6bn8A01 19 Jul, 2018 2.130.10.10 Assigned
6bn8A02 19 Jul, 2018 2.130.10.10 Assigned
6bn8A03 19 Jul, 2018 1.10.150.910 Assigned
6bn8B01 19 Jul, 2018 2.170.150.20 Assigned
6bn8B02 19 Jul, 2018 2.30.130.40 Assigned
6bn8B03 19 Jul, 2018 1.20.58.1480 Assigned
6bn8C01 19 Jul, 2018 1.20.920.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q96SW2 CRBN_HUMAN Homo sapiens Protein cereblon
Q16531 DDB1_HUMAN Homo sapiens DNA damage-binding protein 1
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4