CATH Classification

Domain Context

CATH Clusters

Superfamily LON domain-like
Functional Family Cereblon, isoform CRA_c

Enzyme Information

UniProtKB Entries (1)

Q16531
DDB1_HUMAN
Homo sapiens
DNA damage-binding protein 1

PDB Structure

PDB 6BN8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Plasticity in binding confers selectivity in ligand-induced protein degradation.
Nowak, R.P., DeAngelo, S.L., Buckley, D., He, Z., Donovan, K.A., An, J., Safaee, N., Jedrychowski, M.P., Ponthier, C.M., Ishoey, M., Zhang, T., Mancias, J.D., Gray, N.S., Bradner, J.E., Fischer, E.S.
Nat. Chem. Biol.