PDB Information

PDB6AZV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form.
Nelp, M.T., Kates, P.A., Hunt, J.T., Newitt, J.A., Balog, A., Maley, D., Zhu, X., Abell, L., Allentoff, A., Borzilleri, R., Lewis, H.A., Lin, Z., Seitz, S.P., Yan, C., Groves, J.T.
Proc. Natl. Acad. Sci. U.S.A.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2017-09-13
Resolution2.760
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6azvA01 28 Jun, 2018 1.20.58.480 Assigned
6azvA02 28 Jun, 2018 Holding pen
6azvB01 28 Jun, 2018 1.20.58.480 Assigned
6azvB02 28 Jun, 2018 Holding pen
6azvC01 28 Jun, 2018 1.20.58.480 Assigned
6azvC02 28 Jun, 2018 Holding pen
6azvD01 28 Jun, 2018 1.20.58.480 Assigned
6azvD02 28 Jun, 2018 Holding pen

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14902 I23O1_HUMAN Homo sapiens Indoleamine 2,3-dioxygenase 1
P14902 I23O1_HUMAN Homo sapiens Indoleamine 2,3-dioxygenase 1
P14902 I23O1_HUMAN Homo sapiens Indoleamine 2,3-dioxygenase 1
P14902 I23O1_HUMAN Homo sapiens Indoleamine 2,3-dioxygenase 1
CATH-Gene3D is a Global Biodata Core Resource Learn more...