PDB 5wfr

PDB Links
Overview

PDB Information

PDB	5WFR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling. Burns, M.C., Howes, J.E., Sun, Q., Little, A.J., Camper, D.V., Abbott, J.R., Phan, J., Lee, T., Waterson, A.G., Rossanese, O.W., Fesik, S.W. Anal. Biochem.
Header	Signaling Protein
Released	2017-07-12
Resolution	2.460
CATH Insert Date	03 Jun, 2018

PDB Images (8)

Image of CATH 5wfr

5wfr

PDB 5wfr

Image of CATH 5wfrN

5wfrN

PDB Chain 5wfrN

Image of CATH 5wfrQ

5wfrQ

PDB Chain 5wfrQ

Image of CATH 5wfrR

5wfrR

PDB Chain 5wfrR

Image of CATH 5wfrN01

5wfrN01

CATH Domain 5wfrN01

Image of CATH 5wfrN02

5wfrN02

CATH Domain 5wfrN02

Image of CATH 5wfrQ00

5wfrQ00

CATH Domain 5wfrQ00

Image of CATH 5wfrR00

5wfrR00

CATH Domain 5wfrR00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
N	03 Jun, 2018	Chopped
Q	03 Jun, 2018	Chopped
R	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5wfrN01	28 Jun, 2018	1.20.870.10	Assigned
5wfrN02	28 Jun, 2018	1.10.840.10	Assigned
5wfrQ00	28 Jun, 2018	3.40.50.300	Assigned
5wfrR00	28 Jun, 2018	3.40.50.300	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q07889	SOS1_HUMAN	Homo sapiens	Son of sevenless homolog 1
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas
P01112	RASH_HUMAN	Homo sapiens	GTPase HRas