PDB 5veb

PDB Information

PDB5VEB
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Bialucha, C.U., Collins, S.D., Li, X., Saxena, P., Zhang, X., Durr, C., Lafont, B., Prieur, P., Shim, Y., Mosher, R., Lee, D., Ostrom, L., Hu, T., Bilic, S., Rajlic, I.L., Capka, V., Jiang, W., Wagner, J.P., Elliott, G., Veloso, A., Piel, J.C., Flaherty, M.M., Mansfield, K.G., Meseck, E.K., Rubic-Schneider, T., London, A.S., Tschantz, W.R., Kurz, M., Nguyen, D., Bourret, A., Meyer, M.J., Faris, J.E., Janatpour, M.J., Chan, V.W., Yoder, N.C., Catcott, K.C., McShea, M.A., Sun, X., Gao, H., Williams, J., Hofmann, F., Engelman, J.A., Ettenberg, S.A., Sellers, W.R., Lees, E.
Cancer Discov
HeaderImmune System
Released2017-04-04
Resolution2.340
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
H 14 Nov, 2017 Chopped
L 14 Nov, 2017 Chopped
X 14 Nov, 2017 Chopped
Y 14 Nov, 2017 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5vebA01 10 Dec, 2017 Holding pen
5vebA02 10 Dec, 2017 2.60.40.10 Assigned
5vebB01 10 Dec, 2017 2.60.40.10 Assigned
5vebB02 10 Dec, 2017 2.60.40.10 Assigned
5vebH01 10 Dec, 2017 Holding pen
5vebH02 10 Dec, 2017 2.60.40.10 Assigned
5vebL01 10 Dec, 2017 2.60.40.10 Assigned
5vebL02 10 Dec, 2017 2.60.40.10 Assigned
5vebX00 16 Dec, 2017 Write scan list
5vebY00 16 Dec, 2017 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P55285 CADH6_HUMAN Homo sapiens Cadherin-6
P55285 CADH6_HUMAN Homo sapiens Cadherin-6