PDB Information

PDB5OV7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.
Jost, M., Chen, Y., Gilbert, L.A., Horlbeck, M.A., Krenning, L., Menchon, G., Rai, A., Cho, M.Y., Stern, J.J., Prota, A.E., Kampmann, M., Akhmanova, A., Steinmetz, M.O., Tanenbaum, M.E., Weissman, J.S.
Mol. Cell
HeaderCell Cycle
Released2017-08-28
Resolution2.400
CATH Insert Date14 Nov, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5ov7A01 10 Dec, 2017 3.40.50.1440 Assigned
5ov7A02 10 Dec, 2017 3.30.1330.20 Assigned
5ov7A03 10 Dec, 2017 1.10.287.600 Assigned
5ov7B01 10 Dec, 2017 3.40.50.1440 Assigned
5ov7B02 10 Dec, 2017 3.30.1330.20 Assigned
5ov7B03 10 Dec, 2017 1.10.287.600 Assigned
5ov7C01 10 Dec, 2017 3.40.50.1440 Assigned
5ov7C02 10 Dec, 2017 3.30.1330.20 Assigned
5ov7C03 10 Dec, 2017 1.10.287.600 Assigned
5ov7D01 10 Dec, 2017 3.40.50.1440 Assigned
5ov7D02 10 Dec, 2017 3.30.1330.20 Assigned
5ov7D03 10 Dec, 2017 1.10.287.600 Assigned
5ov7E01 10 Dec, 2017 6.10.280.30 Assigned
5ov7F01 10 Dec, 2017 3.40.50.11480 Assigned
5ov7F02 10 Dec, 2017 3.30.470.20 Assigned
5ov7F03 10 Dec, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain