1 keywords

CATH Domain 5ov7D01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1440 Tubulin/FtsZ, GTPase domain

Domain Context

CATH Clusters

Superfamily Tubulin/FtsZ, GTPase domain
Functional Family Tubulin beta chain

Enzyme Information

UniProtKB Entries (3)

E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
P63043
STMN4_RAT
Rattus norvegicus
Stathmin-4
P81947
TBA1B_BOVIN
Bos taurus
Tubulin alpha-1B chain

PDB Structure

PDB 5OV7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.
Jost, M., Chen, Y., Gilbert, L.A., Horlbeck, M.A., Krenning, L., Menchon, G., Rai, A., Cho, M.Y., Stern, J.J., Prota, A.E., Kampmann, M., Akhmanova, A., Steinmetz, M.O., Tanenbaum, M.E., Weissman, J.S.
Mol. Cell