PDB Information

PDB5NJH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Saez-Calvo, G., Sharma, A., Balaguer, F.A., Barasoain, I., Rodriguez-Salarichs, J., Olieric, N., Munoz-Hernandez, H., Berbis, M.A., Wendeborn, S., Penalva, M.A., Matesanz, R., Canales, A., Prota, A.E., Jimenez-Barbero, J., Andreu, J.M., Lamberth, C., Steinmetz, M.O., Diaz, J.F.
Cell Chem Biol
HeaderStructural Protein
Released2017-03-28
Resolution2.390
CATH Insert Date14 Nov, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5njhA01 10 Dec, 2017 3.40.50.1440 Assigned
5njhA02 10 Dec, 2017 3.30.1330.20 Assigned
5njhA03 10 Dec, 2017 1.10.287.600 Assigned
5njhB01 10 Dec, 2017 3.40.50.1440 Assigned
5njhB02 10 Dec, 2017 3.30.1330.20 Assigned
5njhB03 10 Dec, 2017 1.10.287.600 Assigned
5njhC01 10 Dec, 2017 3.40.50.1440 Assigned
5njhC02 10 Dec, 2017 3.30.1330.20 Assigned
5njhC03 10 Dec, 2017 1.10.287.600 Assigned
5njhD01 10 Dec, 2017 3.40.50.1440 Assigned
5njhD02 10 Dec, 2017 3.30.1330.20 Assigned
5njhD03 10 Dec, 2017 1.10.287.600 Assigned
5njhE01 10 Dec, 2017 6.10.280.30 Assigned
5njhF01 10 Dec, 2017 3.40.50.11480 Assigned
5njhF02 10 Dec, 2017 3.30.470.20 Assigned
5njhF03 10 Dec, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain