1 keywords

CATH Domain 5njhB01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1440 Tubulin/FtsZ, GTPase domain

Domain Context

CATH Clusters

Superfamily Tubulin/FtsZ, GTPase domain
Functional Family Tubulin beta chain

Enzyme Information

UniProtKB Entries (3)

P63043
STMN4_RAT
Rattus norvegicus
Stathmin-4
E1BQ43
E1BQ43_CHICK
Gallus gallus
Uncharacterized protein
Q6B856
TBB2B_BOVIN
Bos taurus
Tubulin beta-2B chain

PDB Structure

PDB 5NJH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Saez-Calvo, G., Sharma, A., Balaguer, F.A., Barasoain, I., Rodriguez-Salarichs, J., Olieric, N., Munoz-Hernandez, H., Berbis, M.A., Wendeborn, S., Penalva, M.A., Matesanz, R., Canales, A., Prota, A.E., Jimenez-Barbero, J., Andreu, J.M., Lamberth, C., Steinmetz, M.O., Diaz, J.F.
Cell Chem Biol