PDB Information

PDB5N84
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity.
Uitdehaag, J.C.M., de Man, J., Willemsen-Seegers, N., Prinsen, M.B.W., Libouban, M.A.A., Sterrenburg, J.G., de Wit, J.J.P., de Vetter, J.R.F., de Roos, J.A.D.M., Buijsman, R.C., Zaman, G.J.R.
J. Mol. Biol.
HeaderTransferase
Released2017-02-22
Resolution2.300
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5n84A01 10 Dec, 2017 3.30.200.20 Assigned
5n84A02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P33981 TTK_HUMAN Homo sapiens Dual specificity protein kinase TTK