PDB 5mev

PDB Information

PDB5MEV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Johannes, J.W., Bates, S., Beigie, C., Belmonte, M., Breen, J., Cao, S., Centrella, P.A., Clark, M.A., Cuozzo, J.W., Dumelin, C.E., Ferguson, A.D., Habeshian, S., Hargreaves, D., Joubran, C., Kazmirski, S., Keefe, A., Lamb, M.L., Lan, H., Li, Y., Ma, H., Mlynarski, S., Packer, M.J., Rawlins, P., Robbins, D.W., Shen, H., Sigel, E.A., Soutter, H.H., Su, N., Trost, D.M., Wang, H., Wickson, K.F., Wu, C., Zhang, Y., Zhao, Q., Zheng, X., Hird, A.
Acs Med.Chem.Lett.
HeaderImmune System
Released2016-11-16
Resolution2.940
CATH Insert Date07 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
H 08 May, 2017 Chopped
L 08 May, 2017 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
5mevA01 16 May, 2017 1.10.437.10 Assigned
5mevH01 16 May, 2017 2.60.40.10 Assigned
5mevH02 16 May, 2017 2.60.40.10 Assigned
5mevL01 16 May, 2017 2.60.40.10 Assigned
5mevL02 16 May, 2017 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog