CATH Classification

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Induced myeloid leukemia cell differentiation protein Mcl-1

Enzyme Information

UniProtKB Entries (2)

P97287
MCL1_MOUSE
Mus musculus
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Q07820
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1

PDB Structure

PDB 5MEV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Johannes, J.W., Bates, S., Beigie, C., Belmonte, M., Breen, J., Cao, S., Centrella, P.A., Clark, M.A., Cuozzo, J.W., Dumelin, C.E., Ferguson, A.D., Habeshian, S., Hargreaves, D., Joubran, C., Kazmirski, S., Keefe, A., Lamb, M.L., Lan, H., Li, Y., Ma, H., Mlynarski, S., Packer, M.J., Rawlins, P., Robbins, D.W., Shen, H., Sigel, E.A., Soutter, H.H., Su, N., Trost, D.M., Wang, H., Wickson, K.F., Wu, C., Zhang, Y., Zhao, Q., Zheng, X., Hird, A.
Acs Med.Chem.Lett.