PDB 5lhi

PDB Information

PDB5LHI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Faga, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiro, P., Villa, M., Botrugno, O.A., Dessanti, P., Minucci, S., Vultaggio, S., Zagarri, E., Varasi, M., Mercurio, C.
J. Med. Chem.
HeaderOxidoreductase
Released2016-07-12
Resolution3.400
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5lhiA01 14 May, 2017 1.10.10.10 Assigned
5lhiA02 14 May, 2017 Holding pen
5lhiA03 14 May, 2017 1.10.287.80 Assigned
5lhiB00 14 May, 2017 1.20.58.1880 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60341 KDM1A_HUMAN Homo sapiens Lysine-specific histone demethylase 1A
Q9UKL0 RCOR1_HUMAN Homo sapiens REST corepressor 1