CATH Domain 5lhiA03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.287	Helix Hairpins
	1.10.287.80	ATP synthase, gamma subunit, helix hairpin domain

Domain Context

CATH Clusters

Superfamily	ATP synthase, gamma subunit, helix hairpin domain
Functional Family	Lysine-specific histone demethylase 1A

Enzyme Information

1.-.-.-

Oxidoreductases.

based on mapping to UniProt O60341

UniProtKB Entries (1)

RCOR1_HUMAN

Homo sapiens

REST corepressor 1

PDB Structure

PDB	5LHI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship. Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Faga, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiro, P., Villa, M., Botrugno, O.A., Dessanti, P., Minucci, S., Vultaggio, S., Zagarri, E., Varasi, M., Mercurio, C. J. Med. Chem.