CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.80 | ATP synthase, gamma subunit, helix hairpin domain |
Domain Context
CATH Clusters
| Superfamily | ATP synthase, gamma subunit, helix hairpin domain |
| Functional Family | Lysine-specific histone demethylase 1A |
Enzyme Information
| 1.-.-.- |
Oxidoreductases.
based on mapping to UniProt O60341
|
UniProtKB Entries (1)
| Q9UKL0 |
RCOR1_HUMAN
Homo sapiens
REST corepressor 1
|
PDB Structure
| PDB | 5LHI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J. Med. Chem.
|